Arinze Okoli

Tittel: Forsker II
Telefon: +47 77 62 08 76
E-post: arinze.okoli@genok.no

» Last ned CV

Dr. Arinze Okoli’s research is at the interface of Microbiology, Systems Biology, Biochemistry, Virology, Biosafety Science and Natural Product research. The biomedical fields are interlinked in the research projects due to his aim to understand complex biological mechanisms through studies of microbial (including virus) physiology, genetics and ecology. His approach is whole organism/cell analyses using analytical techniques in Systems Biology, including Proteomics, Transcriptomics, Bioinformatics and Molecular Biology to understand host-microbe & microbe-environment interactions.

Dr. Okoli received his PhD in 2009 from the University of New South Wales, Sydney, Australia, where he investigated the molecular basis of Enterohepatic Helicobacter species’ adaptations to hosts and environment.

Ongoing projects include

Functional genomics of vaccine relevant and naturally occurring orthopoxviruses
Read more about the project here.

Physiological and molecular aspects of microbial response to glyphosate – (an industrial herbicide and environmental pollutant), and its breakdown product – AMPA (aminomethylphosphonic acid)
Read more about the project here.

Molecular basis for bacteria bio-flocculant production (funded by the South African & Norwegian Cooperation – SANCOOP)
Read more about the project here.

Risk Assessment

Dr. Okoli also provides scientific advices that assist the Norwegian Ministry of Environment in the safety evaluation of (1) genetically modified vaccines and medicinal products; and (2) genetically modified foods and feeds.

Follow this link to GenØks assessment page. Due to strict regulations only the assessments regarding genetically modified foods and feeds will be available for the public.

Peer-reviewed publications

22. Kunle Okaiyeto, Uchechukwu U. Nwodo, Arinze S. Okoli, Leonard V. Mabinya, Anthony I. Okoh (2016). «Studies on a Bioflocculant Production by Bacillus sp. AEMREG7″, Polish Journal of Environmental Studies, 25(1): 236-245.

21. Okaiyeto K, Mabinya LV, Nwodo UU, Okoli AS and Okoh AI (2016). «Implications for public health demands alternatives to inorganic and synthetic flocculants: Bioflocculants as important candidates», MicrobiologyOpen. doi: 10.1002/mbo3.334.

20. Okeke M.I., Okoli A.S., Eze E.N., Ekwueme G.C., Okosa, E.U and Iroegbu C.U (2015). «Antibacterial activity of Citrus limonium fruit juice extract», Pak J Pharm Sci, 28(5), 1567-1571. PMID: 26408878

19. Kunle Okaiyeto, Uchechukwu U. Nwodo, Arinze S. Okoli, Leonard V. Mabinya and Anthony I. Okoh. (2015). «Evaluation of flocculating performance of a thermostable bioflocculant produced by marine Bacillus sp.», Env Tech. 37(14), 1829–1842.

18. Okaiyeto, K., Nwodo, U.U., Mabinya, L.V., Okoli, A.S. and Okoh, A.I. (2015). «Characterization of a Bioflocculant (MBF-UFH) Produced by Bacillus sp. AEMREG7″, Int. J. Mol. Sci. 2015, 16, 12986-13003; doi:10.3390/ijms160612986

17. Okeke, M.I., Okoli, A.S., Nilssen, O., Moens, U., Tryland, M., Bøhn, T., and Traavik, T. (2014). «Molecular characterization and phylogenetics of Fennoscandian cowpox virus isolates based on the p4c and atip genes«. Virology Journal. 2014 Jun 27;11(1):119. doi: 10.1186/1743-422X-11-119.

16. Okoli, A., Raftery M.J. and Mendz, G.L.  «Comparison of Helicobacter bilis-Associated Protein Expression in Huh7 Cells Harbouring HCV Replicon and in Replicon-Cured Cells» National Center for Biotechnology Information 2012, PMID: 22900193

15. Okoli, A., Raftery M.J. and Mendz, G.L. (2012) Effects of human and porcine bile on the proteome of Helicobacter hepaticus Proteome Science, 10:27

14. Tania E. Farrar, Arinze S. Okoli, George L. Mendz. (2011). “Campylobacter spp. Responses to the Environment and Adaptations to Hosts”. In Hin-chung Wong (ed), Stress Response of Foodborne Microorganisms, Nova Science Publishers, Inc. NY, USA, Chapter 8. ISBN: 9781611228106. Access via the publisher here: https://www.novapublishers.com/catalog/product_info.php?products_id=19856

13. Arinze S. Okoli, M.R. Wilkins, M.J. Raftery and G.L. Mendz. (2010). The Response of H. hepaticus To Bovine Bile. J Proteome Res. 9(3):1374-84.

12. Q. V. Tu, Arinze S. Okoli, Z. Kovach and G. L. Mendz. (2009). Hepatocellular Carcinoma: Prevalence of Helicobacter spp. and Molecular Pathogenesis. Future Microbiol. 4:1283-13301.

11. Arinze S. Okoli, C. Armalle and G.L. Mendz. (2009) The Year in Helicobacter: Other Helicobacter species. Helicobacter. 14 (1): 69-74.

10. Megan Duckworth, Arinze S. Okoli and G.L. Mendz. (2009). Novel Helicobacter pylori therapeutic targets: the unusual suspects. Expert Rev. Anti. Infect. Ther. 7(7): 835-867.

9. Arinze S. Okoli (2009). Insight into Host Adaptation of Enterohepatic Helicobacter Bacteria: A molecular study of the response of Helicobacter hepaticus to bile, and the effect of Helicobacter bilis on human hepatoma cells. PhD Thesis. University of New South Wales, Sydney, Australia. VDM Verlag Dr. Muller Aktiengesellschaft & Co. KG. ISBN: 978-3-639-27414-1

8. Arinze S. Okoli, T. Wadstrom and G.L. Mendz. (2007). Bioinformatic Study of Bile Responses in Campylobacterales. FEMS Immunology & Medical Microbiology 49: 101-103.

7. Arinze S. Okoli, E.M. Fox, M.J. Raftery and G.L. Mendz. (2007). Effects of Helicobacter hepaticus on the proteome of HEp-2 cells. Antonie van Leeuwenhoek. 92: 289-300.

6. C.O. Okoli, P. A. Akah, and Arinze S. Okoli (2007). Potentials of leaves of Aspilia africana (Compositae) in wound care: an experimental evaluation. BMC Complement & Alternative Medicine. 7:24. Doi:10.1186/1472-6882-7-24.

5. Arinze S. Okoli and C.U. Iroegbu (2005). In Vitro Antibacterial Activity of Synclisa Scabrida Whole Root Extracts. African Journal of Biotechnology 4: 946-952.

4. Arinze S. Okoli, and C.U. Iroegbu (2004). Evaluation of Extracts of Anthocleista Djalonensis, Nauclea Latifolia and Uvaria Afzalii for Activity against Bacterial Isolates from cases of Non-Gonococcal Urethritis. Journal of Ethnopharmacology. 92: 135-144.

3. Arinze S. Okoli, M.I. Okeke, C.U. Iroegbu and P.U. Ebo (2002). Antibacterial Activity of Harungana madagasceriensis Leaf Extracts. Phytotherapy Research 15: 1-6.

2. M.I. Okeke, C.U. Iroegbu, E.N. Eze, Arinze S. Okoli (2001). Evaluation of Extracts of the Root of Landolphia owerrience for Antibacterial Activity.  Journal of Ethnopharmacology. 78: 119-127.

1. M.I. Okeke, C.U. Iroegbu, C.O. Jideofor, Arinze S. Okoli, and C.O. Esimone (2000). Antimicrobial Activity of Ethanol Extracts of two Indigenous Nigerian Spices. Journal of Herbs, Spices and Medicinal Plants 8: 39-46.